Automating Clinical Trial Planning with Nested Knowledge

April 26, 2023 Nested Knowledge & Adaptic Health are combining forces to maximize chances of clinical trial success. Nested Knowledge, a platform for structuring clinical literature and auto-generating interactive outputs, is pairing with Adaptic Health, an application for modeling recruitment, timelines, and cost in the clinical trial development process.   Clinical trial planning can be […]

Test driving Systematic Review software: What does “Feature Complete” look like?

Systematic Review Software Comparison

Though there are over 240 tools for systematic review on the SR Toolbox, only 24 are functioning, web-based softwares for pre-clinical or clinical review. These range from academic projects to COVID-inspired living visualizations, so not every tool was intended to cover every feature recommended by Mierden/Harrison/Marshall/Kohl, but all tools cover the essential steps of adding studies, screening, and extracting and presenting some sort of review data. Table 4 in the Results section of our freely available feature assessment lays out all the options.


Data extraction, cells

June 3, 2022 This help article is about performing data extraction for meta-analyses in the NK Platform. If you just want basic instructions, feel free to check out this part of our wiki.  Extraction is quite contentious at NK. It is one of those things you either love or hate with the fire of 1000 […]

Paper Spotlight: Mechanical Thrombectomy in Anterior vs. Posterior Stroke

Research question concept map

May 25, 2022 Let’s take a quick peek at an actual manuscript published using our software. Check it out! Seeing a manuscript through to publication is stressful. You have spent months searching, screening, extracting, analyzing, and writing to be at the whim of some random peer reviewers who don’t see your manuscript as the masterpiece […]

Developing Nested Knowledge: 2022 and Beyond

Nested Knowledge Development Timeline - 2020-2022

Looking ahead to 2022, the Nested Knowledge team is excited to bring additional features to the platform over the coming year, namely dual extraction, dual risk of bias, more quality control options, and an advanced organization-level library (including the very exciting “review inspector”).