Nested Knowledge was founded by Keith and Kevin Kallmes,
Two brothers who have spent the past 3 years building a neurovascular-focused research company. While working with organizations as diverse as strategic device companies, research hospitals, private practice clinicians, and medical device startups, Kevin became frustrated with how difficult it was to compare therapies in the clinical literature. Inspired by an internal research tool he used to draft comprehensive literature reviews for clients, he built a research organization visualization for acute ischemic stroke. Kevin presented this to over 30 stroke interventionalists for feedback, and we continue to work with them to create and improve additional interventional nests.
Over the past 6 months, we have built a team of developers, informaticists, statisticians, researchers, and clinical advisers who developed a range of nested visualizations to demonstrate differential efficacy of thrombectomy tools. Currently, we are branching out into related neurovascular research questions. After we create a number of nests, we envision constructing a tool to compare potential patient outcomes based on background characteristics.