Best Practices for NKs AI Tools

Artificial Intelligence in Nested Knowledge

Last Updated: October 6, 2025

Nested Knowledge offers a variety of AI-enhanced tools that make the systematic review process smoother and easier for users. Listed in order of when you would use each tool in the review process, here are our four key AI features:

Validation Studies of AI Tools in Nested Knowledge

Last Updated: June 5, 2025

At Nested Knowledge, we are committed to transparency and rigorous evaluation of our AI-powered review tools. This page compiles validation studies across the core stages of the evidence synthesis workflow: Search, Screening, Data Extraction. For each stage, we provide internal assessments and external, third-party evaluations, including academic reviews, NICE compliance alignment, and independent comparative analyses....

Crafting the Perfect Prompts for Nested Knowledge’s AI Tools

Last Updated: September 25, 2025

Rules of thumb:  4. All prompt-based questions can be run with or without associated annotations, meaning the LLM response will highlight a direct excerpt from the text to inform its response. Selecting to run the LLM without requiring annotations will provide a more generative response, which in some cases, may be more accurate.  Criteria-based Screening...

Guidance on using AI in Nested Knowledge

Last Updated: October 13, 2025

Nested Knowledge employs a number of AI tools at each stage of the review workflow. Here we provide links to guidance on how to use each tool in addition to tips and tricks on best practices and how to get the most out of each tool. Many of the below tools require input of prompts....

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