Cytel and Nested Knowledge Announce Strategic Partnership to Transform Evidence Synthesis for HEOR and HTA Stakeholders

Nested Knowledge partners with Cytel

Cambridge, MA and St. Paul, MN — May 9, 2025 — Cytel, a global leader in data-driven decision-making solutions for life sciences, and Nested Knowledge, the AI-powered platform redefining systematic literature reviews, today announced a strategic partnership aimed at revolutionizing evidence synthesis for Health Economics and Outcomes Research (HEOR) and Health Technology Assessment (HTA).

Join Nested Knowledge at ISPOR EU 2024: AI-Powered Solutions for the HTAR Era

Meet Ranita Tarchand, Dave Thompson, Keith Kallmes, Kevin Kallmes, Jade Thurnham, and Marius Sauca at ISPOR 2024 in Barcelona, Spain. November 17th through 20th.

As we approach ISPOR Europe 2024 in Barcelona on November 17th, we stand at a fascinating intersection of regulatory evolution and technological innovation. This conference comes at a crucial time, just months before the implementation of the EU Health Technology Assessment Regulation (HTAR) – a transformative change in how health technologies are evaluated across the European Union. While policy makers have spent the past three years laying the groundwork for the coming harmonization of health technology assessment, we at Nested Knowledge have also been hard at work developing tools to help our users meet a number of the associated challenges head-on.

Empowering Stroke Research: Dr. Yasmin Aziz’s Journey with Nested Knowledge

Dr. Yasmin Aziz

In the ever-evolving field of stroke research, new questions about different therapies, trial outcomes, and even metrics of procedural success are constantly emerging, meaning that systematic reviews are needed on a consistent basis to extract all information needed to inform both patient care and future research. In these projects, because of the major decisions that may result from the findings and because of how busy stroke physicians are, the efficiency and accuracy are paramount.
Recently, we sat down for a conversation with Dr. Yasmin Aziz, a practicing neurologist and Assistant Professor in the Neurology and Rehabilitation Medicine Department at the University of Cincinnati (UC) Gardner Neuroscience Institute.

NICE Guidelines for AI Methods: The Nested Knowledge Approach

New AI Guidance from NICE

This article outlines how to achieve compliance with HEOR and SLR guidelines for employing AI:
AI Approach: First, we outline our development practices and approach to integrating AI into the human workflows for SLR and evidence synthesis, with a focus on human oversight, transparency, validation, and compliance with emerging industry standards.
NICE Compliance: In part two of this article, we’ll examine how our philosophy stacks up against the latest position statement from the National Institute for Health and Care Excellence (NICE), including AI-enabled practices that fall within specific guidance from this statement.

Introducing Core Smart Tags

Introducing Core Smart Tags If you are familiar with Tagging in Nested Knowledge, you know how integral the process of setting up a tagging hierarchy is to overall study design. If Tagging is new to you, check out this article and then come back to this one! In short, Tagging is the critical function for […]

JCA: How Nested Knowledge Helps

A blog about systematic literature reviews? Yep, you read that right. We started making software for conducting systematic reviews because we like doing systematic reviews. And we bet you do too. If you do, check out this featured post and come back often! We post all the time about best practices, new software features, and upcoming […]

AI for Screening: How is it used, and how can we tell how accurate it is?

A Simple Guide to Understanding AI Screening Models and Cross-Validation in Systematic Literature Reviews (SLRs) Introduction AI is increasingly used in systematic literature reviews (SLRs), and screening is one of its most readily AI-assisted steps. Understanding how to evaluate AI performance in this context is crucial for determining its appropriateness in your review. This guide […]

Validation Summary: Robot Screener’s Performance in Screening Records for Systematic Literature Review and Health Technology Assessment

Systematic literature reviews (SLRs) are the backbone of Health Economics and Outcomes Research (HEOR), playing a vital role in Health Technology Assessments (HTAs). However, the vast quantity of research publications can turn the initial screening of abstracts into a time-consuming roadblock. Nested Knowledge’s (NK) Robot Screener is an AI tool poised to revolutionize this process, […]

Nested Knowledge Will Be At ISPOR 2024

From helping you implement faster AI-assisted workflows which speed up your team by up to 75%, to helping you think through how to design your next project with the new JCA requirements in mind, Nested Knowledge has you covered. If there is a singular through line that ties these top trends together, it’s this: evidence synthesis is getting more complicated, not less.

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