Understanding Deduplication in Nested Knowledge
If you’ve ever uploaded a set of articles into Nested Knowledge and noticed that the numbers shown in your Literature Search, PRISMA diagram, or uploaded files don’t quite match, you’re not alone. Deduplication is a nuanced process, and while Nested Knowledge handles it automatically, there are several key implementation details to ensure deduplication remains sane […]
2025 at Nested Knowledge: A Year of Strategic Growth
2025 at Nested Knowledge: A Year of Strategic Growth As 2025 comes to a close, Nested Knowledge reflects on a year defined not just by growth, but by validation. This was the year our vision for AI-enabled evidence generation moved decisively from promise to proof. At the heart of that progress was a wave of […]
Nested Knowledge and Pharmacy Podcast Network Announce Strategic Collaboration to Advance Evidence-Based Podcasting in Healthcare
PITTSBURGH, PENNSYLVANIA / ACCESS Newswire / December 17, 2025 / The Pharmacy Podcast Network (PPN), the leading audio platform for pharmacy professionals, today announced a strategic collaboration with Nested Knowledge, the premier end-to-end solution for AI-enabled systematic literature reviews and evidence synthesis. Together, the organizations will introduce a new benchmark in healthcare media: evidence-based podcasting. […]
Responsible AI in Evidence Synthesis: How Nested Knowledge Meets the New Standards from Cochrane Joint Statement and RAISE Guidelines
The past year has seen a surge in global attention on the responsible use of AI in systematic reviews. With Cochrane, academic groups, and regulatory-adjacent bodies releasing clearer guidance, including new summaries of the RAISE framework, research organizations are being asked to show exactly how their AI works, how it is evaluated, and where its […]
13 Rapid Reviews in Record Time: Inside the AI-Powered Case Study
13 Rapid Reviews in Record Time: Inside the AI-Powered Case Study Background A global research team sought rapid, structured insights across multiple emerging oncological therapeutic areas (some in rare disease). The goal was to build early-stage evidence assets covering clinical, epidemiologic, and economic evidence available on the research team’s therapies and all comparators in each […]
Where Can You Find Us At ISPOR EU 2025?
Nested Knowledge at ISPOR Europe 2025: Advancing AI in Evidence Synthesis Nested Knowledge is proud to have a major presence at ISPOR Europe 2025, with multiple panels and posters highlighting the validation, application, and impact of artificial intelligence (AI) in health technology assessment (HTA), evidence synthesis, and payer decision-making. From independent validation studies to expert […]
Rapid Review for the Life Sciences
Background In clinical research and strategic decision-making, speed and accuracy in synthesizing evidence are crucial. Traditional systematic literature reviews (SLRs) can take weeks or months, slowing insights into emerging therapeutic areas. To address this challenge, a global life sciences team commissioned Nested Knowledge to run an AI-assisted rapid review on a critical biomarker and therapeutic […]
IEGPs: The Bridge Between Medical Affairs and HEOR
Integrated Evidence Generation Plans (IEGPs) are meant to be the connective tissue across the product lifecycle. Strategic, collaborative plans that guide when, where, and how to generate evidence. In theory, they’re working documents that evolve with your asset. In practice? They’re often PowerPoints filed away on SharePoint, glanced at during meetings, and quickly outdated. But […]
How is SLR used in HTA? A Primer from Nested Knowledge
Why Systematic Literature Reviews Matter in HTA Health Technology Assessment (HTA) decisions are only as strong as the evidence that supports them. That’s why systematic literature reviews (SLRs) are a core requirement across global HTA frameworks. They provide a transparent, reproducible foundation for evaluating the safety, efficacy, and cost-effectiveness of medical interventions. HTA decisions are […]
Canada’s AI Guidance for Systematic Reviews: What CDA’s Position Means for Researchers and HTA Submissions
Back in 2024,when the UK’s NICE released its position statement on the use of artificial intelligence (AI) in health technology assessments (HTAs), Nested Knowledge responded quickly, showing how our platform already aligns with the responsible use of AI in evidence generation. Now, Canada’s Drug Authority (CDA) has followed suit, releasing its own guidance on AI […]
