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Introducing Core Smart Tags
Introducing Core Smart Tags If you are familiar with Tagging in Nested Knowledge, you know how integral the process of setting up a tagging hierarchy
August 27, 2024
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Integrated Evidence Generation Plans (IEGPs) are meant to be the connective tissue across the product lifecycle. Strategic, collaborative plans that guide when, where, and how to generate evidence.
In theory, they’re working documents that evolve with your asset. In practice? They’re often PowerPoints filed away on SharePoint, glanced at during meetings, and quickly outdated.
But when done right, IEGPs can be transformative. They align Medical Affairs, HEOR, RWE, and Clinical teams around a unified vision. Ensuring that every study, every analysis, and every data point serves a broader purpose: delivering the right evidence to the right audience at the right time.
Why IEGPs Matter
IEGPs are not just planning tools, they’re decision-making engines. At each stage of development, they help clarify what questions need answering and what evidence will carry weight. For example, early in development, IEGPs support indication selection and trial design. By Phase 2 and 3, they inform go/no-go decisions, leveraging real-world data (RWD), AI/ML, and external controls. And post-launch, they become critical in preparing for HTA submissions and life cycle management (LCM).
At MAPS 2025, presenters emphasized how IEGPs should support:
When They’re Used and When They Should Be
IEGPs are often drafted in late Phase 2 or early Phase 3, but by then, many pivotal decisions are already locked in. Instead, they should be initiated as early as the preclinical phase, evolving through launch and beyond. As Joint Clinical Assessments (JCAs) become standard in the EU, with just 165 days to submit dossiers post-CHMP, there’s no time to waste for evidence alignment.
How Nested Knowledge Can Help
This is where Nested Knowledge fits in. We make IEGPs dynamic, linking evidence planning to actual evidence generation, in one platform. With NK, teams can collaboratively map questions to studies, literature to outputs, and data to decision points. Our platform connects the dots between systematic reviews, RWE, and submission documentation that way your IEGP becomes more than a slide deck.
Instead of scattered documents and static planning, your evidence strategy becomes centralized, searchable, and shareable, with versioning, source traceability, and continuous updates built in.
So yes, IEGPs should be living documents. Let’s give them a platform that lets them thrive.
Yep, you read that right. We started making software for conducting systematic reviews because we like doing systematic reviews. And we bet you do too.
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Introducing Core Smart Tags If you are familiar with Tagging in Nested Knowledge, you know how integral the process of setting up a tagging hierarchy
