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Introducing Core Smart Tags If you are familiar with Tagging in Nested Knowledge, you know how integral the process of setting up a tagging hierarchy
August 27, 2024
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St. Paul, MN – June 7th, 2025 – Curestack, a leader in real-world data (RWD) infrastructure and AI-powered clinical data platforms, and Nested Knowledge, the premier software platform for living systematic literature reviews and automated evidence synthesis, today announced a strategic partnership to address the growing evidence demands of health technology assessment (HTA), including Joint Clinical Assessment (JCA) requirements in the European Union and the Inflation Reduction Act (IRA) in the United States.
This partnership brings together Curestack’s Interactive Disease Database (IDD) and
analytical platform with Nested Knowledge’s living evidence synthesis platform to enable faster, more transparent, and submission-ready evidence workflows. This partnership will help sponsors centralize and harmonize evidence from all sources, accelerate HTA and IRA deliverables, support dynamic, AI-assisted analytics, and ensure end-to-end traceability and reproducibility.
“Curestack simplifies access to high-quality real-world data. When combined with Nested Knowledge’s evidence tools, we see a clear opportunity to be on the cutting edge of SLR and data collection,” said Omar Dabbous, CEO of Curestack. “This partnership supports a higher quality, more transparent, more accurate and validated source of evidence.”
The new integration will focus on improving workflows for stakeholders in market access, HEOR, and medical affairs. By aligning living literature reviews with structured clinical datasets, the joint solution allows teams to rapidly generate, update, and tailor evidence packages for submissions including EU JCA, ICER reviews, and payer negotiations.
“Omar and the Curestack team bring deep subject matter expertise in evidence development and stakeholder engagement, making them ideal collaborators as we expand our support for health economics and outcomes research,” said Keith Kallmes, President of Nested Knowledge. “Their strategic insight and analytic precision align perfectly with our technology and vision. Together, we’re enabling sponsors to meet the demands of JCA reporting and IRA planning with rigor, speed, and clarity—delivering validated, high-impact outputs from a single, living evidence ecosystem.”
About Curestack
Curestack is a real-world data and AI company empowering clinical teams to structure, analyze, and act on patient-level healthcare data. Through its intuitive platform, Curestack automates the transformation of raw clinical records into analysis-ready data, enabling breakthroughs in research, care delivery, and regulatory-grade evidence generation. Curestack partners with providers, life sciences companies, and technology leaders to build the infrastructure for a learning health system grounded in real-world insights.
About Nested Knowledge
Nested Knowledge is a software company transforming how evidence synthesis is performed and consumed. Their AI-powered platform supports end-to-end workflows for systematic literature reviews, from search to visualization, and offers “living” evidence libraries that update as new data emerges.
For more information, visit https://curestack.net/ or https://nested-knowledge.com/
For media inquiries:
Curestack Media Contact: omar.dabbous@curestack.net
Nested Knowledge Media Contact: contact@nested-knowledge.com
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Introducing Core Smart Tags If you are familiar with Tagging in Nested Knowledge, you know how integral the process of setting up a tagging hierarchy
