Nested Knowledge Blog
A blog about systematic literature reviews?
Yep, you read that right. We started making software for conducting systematic reviews because we like doing systematic reviews. And we bet you do too.
If you do, check out this featured post, as well as other recent posts below, and come back often! We post all the time about best practices, new software features, and upcoming collaborations (that you can join!).
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The Best Questions to Ask Yourself When Starting a Review
At Nested Knowledge, we often say that the difference between a successful and failed evidence synthesis project comes down to how well the Research Question is scoped. Before even launching a review, the most important decision you can make is
More Recent Posts

The Best Questions to Ask Yourself When Starting a Review
At Nested Knowledge, we often say that the difference between a successful and failed evidence synthesis project comes down to how well the Research Question is scoped. Before even launching a review, the most important decision you can make is

Tips and Tricks of Configuring Nested Knowledge’s Tagging Hierarchies for ASTs
Tricks and Tips: The first tip is not about Configuration, but what you do after: Sanity-check a few studies! Sometimes, configuration issues or AI misinterpretations are very easily discoverable by checking just a few studies. If there is an obvious

Bridging Borders: Enhancing Health Technology Assessment (HTAs) Across Geographies
Introduction Health Technology Assessment (HTA) has long been a foundational process in global healthcare systems, serving to evaluate the clinical and economic value of medical interventions and guide coverage, reimbursement, and policy decisions. While HTA is practiced globally, the frameworks

Curestack and Nested Knowledge Announce Strategic Partnership to Power End-to-End Evidence Generation from Real-World Data to Regulatory Submission
Curestack, a leader in real-world data (RWD) infrastructure and AI-powered clinical data platforms, and Nested Knowledge, the premier software platform for living systematic literature reviews and automated evidence synthesis, today announced a strategic partnership to address the growing evidence demands of health technology assessment (HTA), including Joint Clinical Assessment (JCA) requirements in the European Union and the Inflation Reduction Act (IRA) in the United States.

What You Might Have Missed at ISPOR 2025
Ahead of ISPOR 2025, Nested Knowledge took a major step forward in ensuring our mission of making evidence smarter, more accessible, and more transparent with three strategic partnerships with some of the most forward-thinking organizations in the industry. Curta With

Cytel Partners with Nested Knowledge to Power the Next Generation of AI-Enhanced LiveSLR® for HEOR and HTA
Cambridge, MA and St. Paul, MN — May 9, 2025 — Cytel, a global leader in data-driven decision-making solutions for life sciences, and Nested Knowledge, the AI-powered platform redefining systematic literature reviews, today announced a strategic partnership aimed at revolutionizing evidence synthesis for Health Economics and Outcomes Research (HEOR) and Health Technology Assessment (HTA).