Nested Knowledge presents poster at the 2019 annual conference of the Society of Vascular and Interventional Neurology

Nested Knowledge presents poster at the 2019 annual conference of the Society of Vascular and Interventional Neurology
Parvathy Hariharan

Nested Knowledge presents poster at the 2019 annual conference of the Society of Vascular and Interventional Neurology

ST. PAUL, MN: February 3, 2020 – Nested Knowledge, a medical data analytics company that visualizes research data from primary studies in a dynamic and interactive format, presented its research on novel, comprehensive meta-analytic software presentation strategies for stroke therapies at the annual conference of the Society of Vascular and Interventional Neurology between November 20th-23rd, 2019 at Atlanta, GA. This first scientific presentation of our novel interactive visualization strategies represents the most-updated meta-analysis of acute ischemic stroke interventional therapies, and provides proof of concept for the novel strategies used in presenting meta-analytical data.

The poster by Nested Knowledge presented its the network meta-analysis comparing therapies and associated outcomes for acute ischemic stroke in a “nest,” which is a consolidation of information on a given disease state and therapy that is both comprehensive and updatable. Researchers analyzed data from 54 stroke therapy comparison studies with 16,159 patients to confirm that stent retrievers had better odds of good outcome (modified Rankin scale mRS 0-2) and lower chances of mortality than thrombolytic techniques. Thombolysis also had lower chances of achieving full reperfusion of blood flow (Modified treatment in cerebral ischemia (mTICI) score pf 2b/3) in comparison with aspiration, stent retrievers and combination techniques. Most notably, the full, interactive platform described in this poster—unlike with conventional meta-analyses—is presented online and updated periodically by Nested Knowledge, along with full methods, making this a living meta-analysis of stroke therapies. The research was presented in association with Superior Medical Experts, a medical writing company based in St. Paul.

About Nested Knowledge:

Nested Knowledge is a medical publishing and analytics company whose primary activity is providing and iteratively improving a platform that presents scientific research from thousands of primary clinical studies in a dynamic, updatable, interactive visual interface. Our software uses specialized algorithms to complete searches, facilitate data gathering from studies, quality-control inputs, and organize data into structured and updateable visuals in partnership with leading research organizations. Our vision is to gather all clinical outcomes data in a single, central system of record and enable treatment, regulatory, insurance, investment, and R&D decisions to be driven by comprehensive, evidence-based analysis in this centralized platform.

More information on the poster can be found on Page 92 of the SVIN website here.


Keith Kallmes

President, Nested Knowledge



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